P21-activated kinase 3 (PAK3) gene mutations are linked to several neurodevelopmental disorders, but the underlying mechanisms remain unclear.In this study, we used a tetracycline-inducible Frozen Beverage Machines system to control the expression of a mutant PAK3 (mPAK3) protein in immediate early gene, namely cFos, positive cells to disrupt PAK s

Antimicrobial resistance (AMR) is considered a global priority for human health, and REGENERLIFE reducing antimicrobial use in food animals has been suggested as a key area for interventions aiming to reduce resistant infections in humans.In addition to the effect on human health, such interventions may have effects across food animal productivity,

Recent studies have shown an unexpectedly high degree of synapse diversity arising from molecular and morphological differences among individual synapses.Diverse synapse types are spatially distributed within individual dendrites, between different neurons, and across and between brain regions, producing the synaptome architecture of the brain.The

Aquatic organisms have been used to investigate the safety of chemicals worldwide.One such assessment is an algal growth inhibition test.Algal growth inhibition tests are commonly performed using a growth chamber with fluorescent lamps as the lighting source, as test guidelines require continuous uniform fluorescent illumination.However, fluorescen

Point contacts between high anisotropy ferromagnetic SmCo _5 and normal metal Cu are used to achieve a strong spin-population inversion in the contact core.Subjected to microwave irradiation in resonance with the Zeeman splitting in Cu, the inverted spin population relaxes through Ball - Catcher - Leg Guard stimulated spin-flip photon emission, det